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Glutathione

Also known as: L-Glutathione, GSH, Reduced glutathione

A tripeptide antioxidant that neutralizes free radicals and may support skin brightening and detoxification.

antioxidantComedogenic: n/a - protein-based

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What it does

Glutathione is a powerful intracellular antioxidant that scavenges free radicals and reactive oxygen species, protecting skin from oxidative stress. It may also inhibit melanin production and support the skin's natural detoxification processes. In cosmetics, stability is challenging, so formulations often include stabilized or precursor forms.

Benefits

Who it suits

How to use

Use in serums or moisturizers as directed. For stability, choose products in opaque packaging and avoid mixing with vitamin C or other destabilizing actives unless formulation is designed for it.

Pairs well with

Niacinamide, Vitamin E, Ferulic acid

Be careful pairing with

Vitamin C (L-ascorbic acid in unstable forms), High-pH formulations

Safety & cautions

Glutathione is notoriously unstable in cosmetic formulations and easily degrades when exposed to light, heat, or air; efficacy depends heavily on stabilization technology and pH. Oral supplementation data on skin effects is limited; topical evidence is emerging but mixed.

Educational information, not medical advice. Concentration and formulation change how an ingredient behaves.

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