Lactobionic Acid
Also known as: Lactobionic acid, 2-O-β-D-galactopyranosyl-D-gluconic acid
A gentle polyhydroxy acid (PHA) that exfoliates and hydrates without excessive irritation.
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Get the appWhat it does
Lactobionic acid is a first-generation PHA with a large molecular size that exfoliates the skin surface by breaking down corneodesmosomes while penetrating slowly and gently. It also has humectant properties, attracting and binding water to the skin. Its antioxidant capability and lower irritation profile make it suitable for sensitive or compromised skin barriers.
Benefits
- Gentle exfoliation with lower irritation than AHAs/BHAs
- Hydrating due to humectant properties
- Antioxidant protection against free radicals
- Improves skin texture and radiance gradually
- Suitable for sensitive, rosacea-prone, or post-procedure skin
Who it suits
- Sensitive skin
- Rosacea-prone skin
- Compromised/damaged barriers
- Those seeking gentle chemical exfoliation
- Post-procedure or reactive skin
How to use
Apply 2-3 times weekly to clean, dry skin, starting with lower concentrations. Follow with hydrating and occlusive products; use SPF during the day as any exfoliant can increase photosensitivity slightly.
Pairs well with
Hyaluronic acid, Niacinamide, Centella asiatica extract, Ceramides
Be careful pairing with
Other strong chemical exfoliants (high-dose glycolic acid, salicylic acid), Retinoids on same day (can be combined cautiously with experience)
Safety & cautions
Generally well-tolerated, but start with low concentrations (1-2%) and patch test first. May cause mild tingling or redness initially; discontinue if irritation persists. Avoid combining with strong actives if skin is already sensitized.
Educational information, not medical advice. Concentration and formulation change how an ingredient behaves.